Following the success of The Lord of the Rings, Wood has appeared in a wide range of films, including Spy Kids 3D: Game Over (2003), Eternal Sunshine of the Spotless Mind (2004), Sin City (2005), Green Street Hooligans (2005), Everything Is Illuminated (2005), Paris, je t'aime (2006), Bobby (2006), Celeste and Jesse Forever (2012), Maniac (2012), Grand Piano, Cooties, The Last Witch Hunter (2015), The Trust (2016), I Don't Feel at Home in This World Anymore (2017), and Come to Daddy (2019). Wood's voice roles include Mumble in the Happy Feet film franchise (2006-2011), the title protagonist in 9 (2009), Spyro the Dragon in the Legend of Spyro video game trilogy (2006–2008), Beck on Disney XD's Tron: Uprising (2012–2013), and Wirt in the Cartoon Network miniseries Over the Garden Wall (2014). He also played Ryan Newman on the FX dark comedy series Wilfred (2011–2014), for which he received a Satellite Award nomination for Best Actor, and Todd Brotzman in the BBC America series Dirk Gently's Holistic Detective Agency (2016–2017). Wood founded the record label Simian Records in 2005, which was dissolved in 2015.